This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.
General Database Information
The Allen Brain Observatory
The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines.
Topic: Search tools and databases, Teaching
INFRAFRONTIER
INFRAFRONTIER is the European Research Infrastructure for phenotyping and archiving of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using the mouse model.
Topic: Search tools and databases
ECVAM QSAR Model Inventory
EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC).
Topic: Alternative methods
European Consensus-Platform for Alternatives (ECOPA)
Topic: Alternative methods
Replacing Animal Research (formally, Fund for the Replacement of Animals in Medical Experiments (FRAME))
Topic: Alternative methods
Alternatives-NIH-USA-ICCVAM
Topic: Alternative methods
Altbib-Bibliography on Alternatives to Animal Testing
ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.
A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.
Topic: Alternative methods
CAAT-Europe (Centre of Alternatives to Animal Testing)
Topic: Alternative methods, Information on drugs and diseases
UCDavis Centre for Animal Alternatives Information
The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.
Topic: Alternative methods
CELPHEDIA (Creation, Breeding, Phenotyping, Distribution and Archiving of Model Organisms)
CELPHEDIA (Creation, Breeding, Phenotyping, Distribution and Archiving of model organisms) is a national operational research infrastructure distributed over the French territory. Its mission is to support academic and industrial scientific community to accelerate discoveries in biology and improve biomedical research.
Topic: Information on drugs and diseases