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University Biomedical Services (UBS)

 

3Rs

ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines

Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Reduction

Searching for 3Rs Information - Published Literature Sources

The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.  

Topic: Reduction

3Rs Reduction

This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.

Topic: Reduction

Collaborative Approach to Metanalysis

CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.

Topic: Reduction

PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence)
Topic: Reduction

Systematic Review Facility

SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.

Topic: Reduction

The Design of Animal Experiments

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

Topic: Reduction

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Topic: Reduction

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Topic: Reduction

New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction

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