3Rs - search page

There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.

This section contains a selection of resources highlighting the alternatives to using animals in research, testing and teaching.

A group of passionate enrichment advocates from academia and industry are the spark for this effort to ignite and excite the laboratory animal community from top to bottom. 

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) - have been published in the Journal of Cerebral Blood Flow and Metabolism

Kirkstall are a biotechnology company specialising in products and services supporting in-vitro cell culture research and the development of routine in vitro testing.

The term ‘welfare assessment’ applies not only to monitoring animals for signs of pain, suffering and distress associated with procedures, but also to the routine assessment of all animals to check for any health or welfare problems

Establishment of a novel system for the production of large numbers of mouse basophils in vitro.

The aim of the 3R Foundation is to promote alternative research methods to animal experimentation through grants for research projects as well as to implement and promote the 3R principles.

Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.

The Guide has specifically been developed to support untrained database users in finding high quality information on relevant alternative strategies and methods to animal experiments from the wide range of sources available on the web. The Guide provides examples of search procedures, suggested search terms and user guidance.  Target users are scientists, national authorities involved in animal protection and ethical committees verifying that all possible alternatives have been considered before conducting animal experiments.

The careful selection of the method by which animals are killed is imperative to ensure that the animals are given the most humane death possible.

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.