The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.
Search found 71 items
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- (-) Remove Replacement filter Replacement
- (-) Remove Refinement filter Refinement
3Rs
FRAME-Alternatives Lab
Topic: Replacement
3Rs Info Bulletin-Switzerland-Non-invasive electrical monitoring of the population spiking activity in the central nervous system
Topic: Refinement
EPISKIN
EPISKIN, world leader in tissue engineering, offers Human Reconstructed Tissues to the global scientific community - academic and industry - to support research and development activities in Safety and Efficacy
Topic: Replacement
Medical Advances Without Animals Trust (MAWA)
MAWA's aim is to advance medical science to improve human health and therapeutic outcomes without using animals or animal products.
Topic: Replacement
Research Animal Training (RAT)
This website provides a series of resources to support the adoption of best practice for commonly used procedures in animal research.
Topic: Refinement
Alternatives-NIH-USA-ICCVAM-US
A website with explanations and sources of alternatives.
Topic: Replacement
RSPCA Implementing the 3Rs
The RSPCA strongly promote fuller implementation of all 3Rs, and they recognise the work done by other bodies to develop and validate humane alternatives, and to address the current crisis with reproducibility and translatability in the life sciences.
- Replacement: methods which avoid or replace animal use - our principal goal
- Reduction: ensuring that the minimum number of animals is used to answer the scientific question, using effective experimental design and statistical analysis to optimise numbers and avoid wasting animals
- Refinement: reducing suffering and improving welfare throughout animals' lives, including procedures, housing, husbandry and care
Topic: Refinement
Animal Free Research UK
Animal Free Research UK funds research that directly impacts the replacement of animals in biomedical research. Their aim is the replacement of animals in fundamental biomedical research as well as proving that valuable human-relevant science can take place with the use of non-animal methods.
Topic: Replacement
Using 3D Cell Models to Screen Out Ineffective Agents Before Animal Studies
Scientists at the ICR are growing spheres of cancer cells in the laboratory which are designed to mimic the properties of solid tumours.
Topic: Replacement
Pain and Laboratory Animals: Publication Practices for Better Data Reproducibility and Better Animal Welfare
Topic: Refinement
InVitroJobs
Internet platform for animal free research (German site).
Topic: Replacement
RSPCA Reduce Suffering Welfare Assessment
The term ‘welfare assessment’ refers to monitoring animals for signs of pain, suffering and distress associated with procedures and their effects, as well as to the day-to-day assessment of all animals to see how they are coping with their environment and to detect health or welfare issues. Indicators of positive wellbeing, such as appropriate levels of grooming and social interaction, should also be included when devising welfare assessment protocols.
Topic: Refinement