3Rs - search page

a database of ideas (with instructions) for making enrichment items for a variety of species.

The Classic AVs database complements NORINA by providing information on audiovisual products produced some years ago, using technology which has been surpassed by modern digital techniques.

The website LAS interactive (LAS = Laboratory Animal Science) contains a wide range of information on animals in research and on scientific methods in animal experiments.

Replacing Animal Research (Formally FRAME) carries out both lab-based and office-based research. Click on the links  for more information.

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

This website provides a series of resources to support the adoption of best practice for commonly used procedures in animal research.

The RSPCA  strongly promote fuller implementation of all 3Rs, and they recognise the work done by other bodies to develop and validate humane alternatives, and to address the current crisis with reproducibility and translatability in the life sciences.

• Replacement: methods which avoid or replace animal use - our principal goal

• Reduction: ensuring that the minimum number of animals is used to answer the scientific question, using effective experimental design and statistical analysis to optimise numbers and avoid wasting animals

• Refinement: reducing suffering and improving welfare throughout animals' lives, including procedures, housing, husbandry and care

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers