3Rs - search page

The aim of the 3R Foundation is to promote alternative research methods to animal experimentation through grants for research projects as well as to implement and promote the 3R principles.

Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.

Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

The careful selection of the method by which animals are killed is imperative to ensure that the animals are given the most humane death possible.

This gateway provides a place for researchers funded by the NC3Rs to promote the 3Rs impact of their work, and publish rapidly, in an open and transparent manner.

Norecopa has constructed four databases, which together with all the text on this website can be searched simultaneously using the search field at the top of every page.

SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.

Considerable progress has been made over the last decade in preventing or alleviating pain. In particular, there is now considerable opportunity to minimise or eliminate pain following surgical procedures. 

Exploring alternatives to gavage for oral administration

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Research by Dr Jeffrey Mogil and colleagues, McGill University, has demonstrated that changes in facial expression provide a reliable and rapid means of assessing pain in mice, rabbits and rats.