Training: Mouse Genetics and Colony Management for Researchers

This course explores more complex genetic topics, including multiple allele crosses, complex disease models and will inform breeding strategies and experimental design rather than give a complete guide to the molecular biology. Our team of experienced trainers will support you to examine how different modifications lead to different breeding strategies, the importance of genetic consistency and integrity and different modes of inheritance. There will be multiple workshops throughout the course and a focus on troubleshooting unexpected issues when looking after Genetically Altered (GA) mouse lines.

Who is this for?

• Colony Managers
• Researchers
• PhD Students

After the course, you will be able to:

• Understand genetic drift and how to maintain the genetic integrity of simple and complex GA lines
• Understand GA nomenclature and why it is important
• Predict the outcomes of genetic crosses involving multiple alleles, including chromosomal linkage and sex-linked genes
• Perform multiple allele inheritance and breeding calculations
• Understand the fundamentals of different methods that give rise to GA mouse strains
• Troubleshoot breeding and colony maintenance issues
• Know the basics of breeding conditional transgenic models
• Discuss blinding and randomising GA experiments

Mouse Genetics and Colony Management for Researchers | Mary Lyon Centre