3Rs - search page

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

Official Journal of the International Society for Applied Ethology (ISAE) An international journal reporting on the application of ethology to animals managed by humans.

By generating and making public data that indicates how cells respond to various genetic and environmental stressors, the LINCS project will help us gain a more detailed understanding of cell pathways and aid efforts to develop therapies.

Welcome to the Zika experimental science team (ZEST) data portal. Given the urgency of the ongoing Zika virus epidemic, we are making our study results available in real-time. Each study and its available data are shown.

This website appears to be temporarily unavailable. 6th October 2023