3Rs - search page

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research. 

Go3R is a sematic search engine to avoid animal experiments.

TSAR is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.   

In collaboration with the Animal Welfare Information Center at the US Department of Agriculture in Beltsville, USA has produced a database which provides an overview of guidelines, databases, journals, email lists, regulations and policies which may help researchers to implement the 3Rs when planning research that may involve animals. The database is called 3R Guide.

The aim of 3R Guide is to provide a 'one-stop shop' for researchers who need to gain an overview of available 3R resources.

ICLAS is an international scientific organization dedicated to advancing human and animal health by promoting the ethical  care and use of laboratory animals in research worldwide.