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The Mandatory Alternatives Petition seeks to change the way drug testing is done in laboratories before drugs are tested on people.

Scientists at the ICR are growing spheres of cancer cells in the laboratory which are designed to mimic the properties of solid tumours.

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.

Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.

A website with explanations and sources of alternatives.

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations in order to ensure worldwide acceptance.

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

Humane Endpoints Website is provided by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.

The aim of "InVitroJobs" is to enable researchers to access this branch of research more easily. Alongside the job search portal, the site maintains an up-to-date list of research groups active in the development of animal-free techniques. The primary aims of this list are to advertise job vacancies, to provide students with the opportunity to contact these research groups directly to obtain information for thesis assignments and to promote cooperation, networking and the exchange of ideas between researchers. 

A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research.