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University Biomedical Services (UBS)



Medical Advances Without Animals Trust (MAWA)

MAWA's aim is to advance medical science to improve human health and therapeutic outcomes without using animals or animal products.

Topic: Replacement

European Consensus-Platform for Alternatives (ECOPA)

The primary aim of ECOPA is to promote "the three Rs" (Replacement, Reduction and Refinement) in the use of animals in research, testing, education and training in Europe.

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Mandatory Alternatives Petition (US)

The Mandatory Alternatives Petition seeks to change the way drug testing is done in laboratories before drugs are tested on people.

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Using 3D Cell Models to Screen Out Ineffective Agents Before Animal Studies

Scientists at the ICR are growing spheres of cancer cells in the laboratory which are designed to mimic the properties of solid tumours.

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FRAME-Alternatives Lab

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

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Ethical Science Education (Library of Alternatives for Disection)

US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.

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Plan to Replace Animal Use Shared at Public Forum

Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.

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A website with explanations and sources of alternatives.

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Research Animal resources (US)

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

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International Cooperation on Alternative Test Methods (ICATM)

To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations in order to ensure worldwide acceptance.

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Alternatives Test Methods Table-Canadian 3Rs Microsite

The Alternative Test Methods Table is a resource for investigators and regulators on the validation and regulatory status of alternatives to animal-based regulatory test methods.

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RSPCA-Useful Alternative Approaches

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

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