SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.
- (-) Remove Reduction filter Reduction
- (-) Remove Rat filter Rat
- (-) Remove Fish filter Fish
- (-) Remove Naked mole-rat filter Naked mole-rat
3Rs
"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.
Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
Species specific
The Sanger Institute started the zebrafish genome sequencing project in 2001 and has generated several genome assemblies of the Tuebingen strain. After the release of Zv9, the zebrafish genome project joined the Genome Reference Consortium (GRC) for further improvement and ongoing maintenance. The GRC has now released a new reference assembly, GRCz11.
According to a new study in eLife, arthritis is much more widespread in the animal kingdom than previously suspected.
The recent development of skin swabbing techniques - which produce sufficient DNA for PCR amplification - potentially offers a refined procedure with enormous impact for fish welfare.