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University Biomedical Services (UBS)

 

3Rs

Systematic Review Facility

SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.

Topic: Reduction

The Design of Animal Experiments

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

Topic: Reduction

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Topic: Reduction

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Species specific

Zebrafish Genome Project

The Sanger Institute started the zebrafish genome sequencing project in 2001 and has generated several genome assemblies of the Tuebingen strain. After the release of Zv9, the zebrafish genome project joined the Genome Reference Consortium (GRC) for further improvement and ongoing maintenance. The GRC has now released a new reference assembly, GRCz11.

Topic: Fish

Fish Arthritis Research

According to a new study in eLife, arthritis is much more widespread in the animal kingdom than previously suspected.

Topic: Fish

NC3Rs- Quantifying the Potential of Skin Swabbing as a Refinement for DNA Sampling of Laboratory Fish

The recent development of skin swabbing techniques - which produce sufficient DNA for PCR amplification - potentially offers a refined procedure with enormous impact for fish welfare.

Topic: Fish

RSPCA- Guidance on the Housing and Care of Zebrafish
Topic: Fish

Evaluating and Optimizing Fish Health and Welfare During Experimental Procedures  
Topic: Fish

Naked Mole-Rat Initiative
Topic: Naked mole-rat

Standardized Welfare Terms for the Zebrafish Community
Topic: Fish

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