Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
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3Rs
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
Discipline tool
The Foundation for Liver Research UK was established in 1974 to develop and extend research into diseases of the human liver and to enhance medical research generally.
CLDF supports a wide range of projects, including clinical and laboratory-based research, lately moving into social research which looks at topics such as how to improve quality of life.