Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
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3Rs
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
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GENETICS is published by the Genetics Society of America, a scholarly society that seeks to deepen our understanding of the living world by advancing our understanding of genetics
Ubiquity Genomics provides high-quality CATCH-Seq probes, customized for your genomic regions of interest. These kits enable targeted enrichment of next-generation sequencing libraries for contiguous blocks of the genome at a fraction of the cost of oligonucleotide pools. CATCH-Seq probes can be synthesized for any species for which there are mapped genomic clones available (BACs or fosmids).
Inherited diseases are widespread among purebred dog populations and represent a significant welfare issues for afflicted breeds.