The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research.
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3Rs
Recommended Dose Volumes for Common Laboratory Animals
Topic: Reduction
ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines
Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.
Topic: Reduction
Searching for 3Rs Information - Published Literature Sources
The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.
Topic: Reduction
3Rs Reduction
This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.
Topic: Reduction
Collaborative Approach to Metanalysis
CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.
Topic: Reduction
Discipline tool
Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology
JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology
Danish 3R Center-Establishment of an Invitro Model for Diabetic Atherosclerosis
Topic: Diabetes
Glasgow Caledonian University-Skin Tissue Stem Cells
Topic: Diabetes
IMPROVE-ing Animal Welfare in Experimental Stroke Research
Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
Topic: Cardiology