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3Rs

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Topic: Reduction

New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction

Animal Tissue Database

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

Topic: Reduction

RSPCA-Research Integrity

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

Topic: Reduction

Discipline tool

Human Biological Data Exchange
Topic: Diabetes

Invitro Models of Diabetes
Topic: Diabetes

IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

Stem Cell Research- Diabetes Research
Topic: Diabetes

Foundation for Biomedical Research- How Animal Testing and Research is Advancing Treatments for Type 2 Diabetes
Topic: Diabetes

Liverpool University Vetschool Cardiology Department
Topic: Cardiology

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