3Rs - search page

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

SEARCHBreast is a resource to facilitate sharing of archived material derived from in vivo breast cancer models.

On this page you will find analysis of global research on preventing cancer. We analyse this research so you have access to the best cancer prevention advice in the world.

Excellent standards of animal care are fully consistent with the conduct of high quality cancer research.

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.