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General Database Information
Three Rs Resources
The Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART) and the Ministry for Primary Industries have produced a series of booklets on the application of the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching.
- Cell-based Disease Models (replacement)
- Computer Assisted Learning (replacement)
- Mannequins and Dummies (replacement)
- Alternatives to shellfish toxicity testing (replacement)
- Fireflies to the rescue (reduction)
- Mathematical models (reduction)
- Tissue sharing (reduction)
- Simple ingenuity (refinement)
- Non-Invasive Methods (refinement)
- Living syringes (refinement)
- Oil emulsified gels (refinement)
ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.
A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.
The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.
ICLAS is an international scientific organization dedicated to advancing human and animal health by promoting the ethical care and use of laboratory animals in research worldwide.
10th World Congress Proceedings/Abstract Book Available Online
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.