3Rs - search page

Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.

Initiate activities that may lead to the immediate implementation of the 3Rs.

The Xenopus Model Welfare Organization will make the use of xenopus as a model organism better by promoting model specific, species specific knowledge and making that knowledge readily available to all stakeholders, including researchers, animal care supervisors, veterinarians, IACUC’s, and government oversight entities. It will influence the care, well-being, and welfare of xenopus as a model for years to come. It will be a compassionate entity that supports the care of xenopus frogs in research institutions and supports the people using xenopus by promoting science based, practical knowledge that can be used by all.

Xenbase's mission is to provide the international research community with a comprehensive, integrated and easy to use web based resource that gives access the diverse and rich genomic, expression and functional data available from Xenopus research. Xenbase also provides a critical data sharing infrastructure for many other NIH-funded projects, and is a focal point for the Xenopus community. In addition to our primary goal of supporting Xenopus researchers, Xenbase enhances the availability and visibility of Xenopus data to the broader biomedical research community.