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General Database Information
AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.
ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.
Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.
Initiate activities that may lead to the immediate implementation of the 3Rs.
The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.
Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial.
CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.