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Discipline tool
General Database Information
Initiate activities that may lead to the immediate implementation of the 3Rs.
The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.
Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial.
CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.
Three Rs Resources
The Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART) and the Ministry for Primary Industries have produced a series of booklets on the application of the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching.
- Cell-based Disease Models (replacement)
- Computer Assisted Learning (replacement)
- Mannequins and Dummies (replacement)
- Alternatives to shellfish toxicity testing (replacement)
- Fireflies to the rescue (reduction)
- Mathematical models (reduction)
- Tissue sharing (reduction)
- Simple ingenuity (refinement)
- Non-Invasive Methods (refinement)
- Living syringes (refinement)
- Oil emulsified gels (refinement)