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University Biomedical Services (UBS)



Searching for 3Rs Information - Published Literature Sources

The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.  

Topic: Reduction

3Rs Reduction

This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.

Topic: Reduction

Collaborative Approach to Metanalysis

CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.

Topic: Reduction

Systematic Review Facility

SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.

Topic: Reduction

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction

RSPCA-Research Integrity

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

Topic: Reduction


EPISKIN, world leader in tissue engineering, offers Human Reconstructed Tissues to the global scientific community - academic and industry - to support research and development activities in Safety and Efficacy

Topic: Replacement

Animal Free Research UK

Animal Free Research UK funds research that directly impacts the replacement of animals in biomedical research. Their aim is the replacement of animals in fundamental biomedical research as well as proving that valuable human-relevant science can take place with the use of non-animal methods.

Topic: Replacement


StudySwap is a platform hosted on the Center for Open Science’s Open Science Framework site, enables users to post their research “haves” and “needs,” with the goal of helping scientists exchange resources and find suitable collaborators for replication studies.

Topic: Reduction

Maximising the 3Rs Impact of NC3Rs-Funded Research

This gateway provides a place for researchers funded by the NC3Rs to promote the 3Rs impact of their work, and publish rapidly, in an open and transparent manner.

Topic: Refinement