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3Rs

Analgesia and Pain Assessment-NC3Rs

Considerable progress has been made over the last decade in preventing or alleviating pain. In particular, there is now considerable opportunity to minimise or eliminate pain following surgical procedures. 

Topic: Refinement

StudySwap

StudySwap is a platform hosted on the Center for Open Science’s Open Science Framework site, enables users to post their research “haves” and “needs,” with the goal of helping scientists exchange resources and find suitable collaborators for replication studies.

Topic: Reduction

Enrichment Record US

A group of passionate enrichment advocates from academia and industry are the spark for this effort to ignite and excite the laboratory animal community from top to bottom. 

Topic: Refinement

FRAME

FRAME carries out both lab-based and office-based research. Click on the links  for more information.

Topic: Refinement

Recommended Dose Volumes for Common Laboratory Animals

The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research. 

Topic: Reduction

Laboratory Animal Anaesthesia for Minor Procedures-EU Module 20 Video
Topic: Refinement

Assessing the Health and Welfare of Laboratory Animals

The AHWLA website makes use of video material to better illustrate points referenced in its tutorials.

Topic: Refinement

Procedures With Care Website

This website provides a series of resources to support the adoption of best practice for commonly used procedures in animal research.

Topic: Refinement

ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines

Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Reduction

Grimace Scales Research

Research by Dr Jeffrey Mogil and colleagues, McGill University, has demonstrated that changes in facial expression provide a reliable and rapid means of assessing pain in mice, rabbits and rats.

Topic: Refinement

3Rs Swiss Foundation

The aim of the 3R Foundation is to promote alternative research methods to animal experimentation through grants for research projects as well as to implement and promote the 3R principles.

Topic: Refinement

Recognition and Prevention of Pain EU module 5 Newcastle University
Topic: Refinement

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