Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research.
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3Rs
Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively
Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers
Topic: Reduction
SABRE Research UK
Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.
Topic: Reduction
Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies
There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.
Topic: Reduction
New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction
General Database Information
International Council for Lab Animal Science (ICLAS)
ICLAS is an international scientific organization dedicated to advancing human and animal health by promoting the ethical care and use of laboratory animals in research worldwide.
Topic: "Three Rs"
3Rs-Centre Utrecht Life Sciences (ULS)
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.
Topic: "Three Rs"
Swedish 3Rs centre
Topic: "Three Rs"
National Centre for the Replacement Refinement and Reduction of Animals in Research (NC3Rs)
Topic: "Three Rs"
PREPARE (Planning Research and Experimental Procedures on Animals)
Recommendations for Excellence: as part of ongoing efforts to reduce waste and increase the reproducibility of animal research and testing, a group of experts led by the Secretary of Norecopa has produced a set of guidelines for planning animal experiments
Topic: "Three Rs"
Alternatives to laboratory Animals (ATLA)
ATLA is published by FRAME, and has been a key scientific journal in the field of laboratory animal alternatives for more than 30 years. Circulated worldwide, ATLA is distributed to individuals, organisations and institutions. It covers the latest research relating to alternatives to the use of laboratory animals.
Topic: Journals, Teaching