The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research.
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3Rs
Recommended Dose Volumes for Common Laboratory Animals
Topic: Reduction
ARRIVE (Animal Research: Reporting of In Vivo Experiments) Guidelines
Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.
Topic: Reduction
Searching for 3Rs Information - Published Literature Sources
The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.
Topic: Reduction
3Rs Reduction
This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.
Topic: Reduction
Collaborative Approach to Metanalysis
CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.
Topic: Reduction
General Database Information
Dutch 3Rs Centre- Utrecht Life Sciences
Topic: "Three Rs"
InVitro Jobs
The aim of "InVitroJobs" is to enable researchers to access this branch of research more easily. Alongside the job search portal, the site maintains an up-to-date list of research groups active in the development of animal-free techniques. The primary aims of this list are to advertise job vacancies, to provide students with the opportunity to contact these research groups directly to obtain information for thesis assignments and to promote cooperation, networking and the exchange of ideas between researchers.
Topic: Portals and Websites
NC3Rs: National Centre for Three Rs, UK
A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research.
Topic: Portals and Websites
The Federation of Laboratory Animal Science Associations (FELASA)
Topic: "Three Rs"
EURL ECVAM Tracking System on Alternative Methods Towards Regulatory Acceptance (TSAR)
TSAR is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.
Topic: Portals and Websites