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Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.
Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.
Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.