Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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IMPROVE-ing Animal Welfare in Experimental Stroke Research
Topic: Cardiology
Jax Phenotype-Cardiovascular
Topic: Cardiology
Liverpool University Vetschool Cardiology Department
Topic: Cardiology
Penn Vet School Cardiology Research
Topic: Cardiology
Journal of Veterinary Cardiology
Topic: Cardiology
Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology
JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology
General Database Information
Home Office Legislation
The use of animals in scientific research remains a vital tool in improving our understanding of how biological systems work both in health and disease, and in the development of new medicines, treatments and technologies. Underpinning this research is a strong commitment to maintaining a rigorous regulatory system which ensures that animal research is carried out only where no practicable alternative exists and under controls which keep suffering to a minimum. This is achieved through robustly applying the principles of the 3Rs to all research proposals involving the use of animals.
Topic: Ethics
Guidelines From The British Psychological Society on the Welfare of Animals in Psychology
Guidlines from the British Psychological Society's Standing Advisory Committee on the Welfare of Animals in Psychology. This was developed in cooperation with EPS.
Topic: Ethics
The Federation of Laboratory Animal Science Associations (FELASA)
Topic: "Three Rs"
CAMARADES
The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.
Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial.
CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.
Topic: Other Resources
Understanding Animal Research
Understanding Animal Research aim to provide all you want to know about animal research, whether you are a concerned member of the public or have a special interest.
Topic: Ethics