Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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ALTEX publishes original articles, short communications, and reviews, as well as news and comments, meeting reports, and book reviews. Animal experiments are defined by the editors as all experimental procedures involving the use of animals in testing, research, and education, or to obtain tissues, organs, and other animal derived products that may cause pain or distress to animals..
AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.
CCAC promotes the application of Three Rs in Canada. Through a website it provides the latest information on the Three Rs, a search tool and a search guide.
Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.