3Rs - search page

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.

Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.

CAAT is an academic, science based centre within the John Hopkins Bloomberg School of Public Health in the USA and the University of Konstanz in Germany which is  dedicated to the promotion of research intoin vitro and other alternative techniques, Three Rs education and information.

Consensus meetings on the care and use of fish, wildlife and agricultural animals in research is provided by Norecopa. It contains presentations, guidelines and consensus statements from four international meetings covering all Three Rs, is in English and free of charge.

Initiate activities that may lead to the immediate implementation of the 3Rs.

CCAC promotes the application of Three Rs in Canada. Through a website it provides the latest information on the Three Rs,   a search tool and a search guide. 

Produced by Norecopa containing sort films, which alternatively can be viewed as slide series, illustrating common techniques. It is in English and free of charge.

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced. 

The website is maintained by Norecopa. It covers all Three Rs, is in English and free of charge.