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3Rs

Ethical Science Education (Library of Alternatives for Disection)

US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.

Topic: Replacement

Animal Tissue Database

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

Topic: Reduction

Plan to Replace Animal Use Shared at Public Forum

Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.

Topic: Replacement

RSPCA-Research Integrity

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

Topic: Reduction

Alternatives-NIH-USA-ICCVAM-US

A website with explanations and sources of alternatives.

Topic: Replacement

Research Animal resources (US)

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

Topic: Replacement

Simian Laboratory Europe (Silabe)

Silabe offers a large range of NonHuman Primate bioproducts to academic research institutes and companies in the field of Science and Health.

Topic: Reduction

International Cooperation on Alternative Test Methods (ICATM)

To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations in order to ensure worldwide acceptance.

Topic: Replacement

StudySwap

StudySwap is a platform hosted on the Center for Open Science’s Open Science Framework site, enables users to post their research “haves” and “needs,” with the goal of helping scientists exchange resources and find suitable collaborators for replication studies.

Topic: Reduction

Alternatives Test Methods Table-Canadian 3Rs Microsite

The Alternative Test Methods Table is a resource for investigators and regulators on the validation and regulatory status of alternatives to animal-based regulatory test methods.

Topic: Replacement

RSPCA-Useful Alternative Approaches

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

Topic: Replacement

Recommended Dose Volumes for Common Laboratory Animals

The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research. 

Topic: Reduction

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