Research published in Scientific Reports describes a new ultra lightweight system for recording neural activity in the brains of mice.
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MouseAGE is opening a call for European researchers to establish their infrastructure needs in the area of ageing and age-related disorders at the preclinical stage with a view to coordinate efforts for applications for funding.
General Database Information
Initiate activities that may lead to the immediate implementation of the 3Rs.
The use of animals in medical and pharmaceutical research is essential to the understanding of disease and the safe development of medicines.
The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines.
ATLA is published by FRAME, and has been a key scientific journal in the field of laboratory animal alternatives for more than 30 years. Circulated worldwide, ATLA is distributed to individuals, organisations and institutions. It covers the latest research relating to alternatives to the use of laboratory animals.
Three Rs Resources
The Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART) and the Ministry for Primary Industries have produced a series of booklets on the application of the three Rs (replacement, reduction and refinement) in the use of animals in research and teaching.
- Cell-based Disease Models (replacement)
- Computer Assisted Learning (replacement)
- Mannequins and Dummies (replacement)
- Alternatives to shellfish toxicity testing (replacement)
- Fireflies to the rescue (reduction)
- Mathematical models (reduction)
- Tissue sharing (reduction)
- Simple ingenuity (refinement)
- Non-Invasive Methods (refinement)
- Living syringes (refinement)
- Oil emulsified gels (refinement)