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Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) have been published in the Journal of Cerebral Bloodflow and Metabolism.
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The Canadian Centre for Alternatives to Animal Methods (CCAAM) and the Canadian Centre for the Validation of Alternative Methods (CaCVAM) aim to develop, validate, and promote non-animal, human biology-based platforms in biomedical research, education, and chemical safety testing.