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3Rs
Blood sampling can be stressful for laboratory animals because of the handling, restraint, anaesthesia or discomfort associated with a particular technique
The suffering that animals experience when they are used in research and testing is a very serious concern. We believe that every possible step must be taken to reduce animal suffering to an absolute minimum.
The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) - have been published in the Journal of Cerebral Blood Flow and Metabolism
Good training in non-aversive handling has benefits for the animal, for the handler and for the reliability of data gained in experiments.
In 2008, the UFAW/RSPCA Rabbit Behaviour and Welfare Group produced a resource that sets out practical guidance on fulfilling the basic needs of the rabbit.
Collecting blood for serology testing from research animals can be a challenging process that leads to increased stress in your animal. Exclusive to Charles River, our HemaTIP™ microsampler simplifies this process by placing the collection media on the tip of an easy-to-hold stylus.
There are several stages to consider when planning and carrying out studies involving animals to establish, implement and refine humane endpoints.
A resource from the research animals department on how housing and care can be refined to reduce suffering and improve welfare of animal species.
General Database Information
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The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre is affiliated with Utrecht Life Sciences and provides information and advice to the Animal Welfare Body of both Utrecht University and the University Medical Centre Utrecht.