3Rs - search page

The Classic AVs database complements NORINA by providing information on audiovisual products produced some years ago, using technology which has been surpassed by modern digital techniques. We offer this collection for those who wish to continue to use classic technology.

AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals.

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation. 

Vaccination of animals against disease protects them from suffering. However, this comes with an animal welfare cost - the safety and efficacy of vaccines is assessed in experimental animals and the tests involved can cause significant pain and distress. There is an ethical dilemma in protecting one set of animals at the expense of others but implementation of the 3Rs can help to resolve this. The research animals department works with researchers involved in vaccine testing and regulators to promote the 3Rs in this important area.

Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.

The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan 
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators

Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.