In the regulatory assessment of chemicals (e.g. under REACH), (Q)SAR models are playing an increasingly important role in predicting properties for hazard and risk assessment.
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3Rs
EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC)
Topic: Replacement
3R-INFO-BULLETIN Swiss 3Rs
Establishment of a novel system for the production of large numbers of mouse basophils in vitro.
Topic: Replacement
Advancing scientific research and education with peer-reviewed video on human stem cells differentiation
Topic: Replacement
NORINA (A Norwegian Inventory of Audiovisuals)
NORINA is an English-language database containing information on over 3,500 audiovisual aids.
Topic: Replacement
American Fund for Alternatives to Animal Research (AFAAR)
AFAAR first helped make history by funding a landmark alternative to the infamous Draize rabbit eye test, later adopted by some major product and cosmetics companies.
Topic: Replacement
Medical Advances Without Animals Trust (MAWA)
MAWA's aim is to advance medical science to improve human health and therapeutic outcomes without using animals or animal products.
Topic: Replacement
European Consensus-Platform for Alternatives (ECOPA)
The primary aim of ECOPA is to promote "the three Rs" (Replacement, Reduction and Refinement) in the use of animals in research, testing, education and training in Europe.
Topic: Replacement
Mandatory Alternatives Petition (US)
The Mandatory Alternatives Petition seeks to change the way drug testing is done in laboratories before drugs are tested on people.
Topic: Replacement
General Database Information
Classic Audiovisual Database-Norina
The Classic AVs database complements NORINA by providing information on audiovisual products produced some years ago, using technology which has been surpassed by modern digital techniques. We offer this collection for those who wish to continue to use classic technology.
Topic: Search tools and databases
EU 3Rs databases
EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation.
Topic: Search tools and databases
NC3Rs Experimental Design Assistant
Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.
The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators
Topic: Search tools and databases
UKCRC Tissue Directory and Coordination Centre
Find Human tissue samples online using the UKCRC Tissue Directory.
Topic: Search tools and databases