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Exploring alternatives to gavage for oral administration

Research by Dr Jeffrey Mogil and colleagues, McGill University, has demonstrated that changes in facial expression provide a reliable and rapid means of assessing pain in mice, rabbits and rats.

a database of ideas (with instructions) for making enrichment items for a variety of species.

EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation. 

This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.

 Find Human tissue samples online using the UKCRC Tissue Directory.

The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines. 

By generating and making public data that indicates how cells respond to various genetic and environmental stressors, the LINCS project will help us gain a more detailed understanding of cell pathways and aid efforts to develop therapies.

INFRAFRONTIER is the European Research Infrastructure for phenotyping and archiving of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using the mouse model.

Has over 5 million more abstracts than PubMed.