3Rs - search page

The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research. 

Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

The I3R group produced the first edition of this document in January 2001 to assist researches and information professionals in the pharmaceutical industry.  

This site provides an interactive short course on experimental design for research scientists working with laboratory animals. The aim is to reduce the number of animals which are used, improve the quality of the science and save time, money and other scientific resources.

CAMARADES provides a supporting framework for groups involved in the systematic review and meta-analysis of data.

The Web of Science® (formerly Web of Knowledge) is today's premier research platform, helping you quickly find, analyze, and share information in the sciences, social sciences, arts, and humanities. You get integrated access to high quality literature through a unified platform that links a wide variety of content with one seamless search.

Go3R is a sematic search engine to avoid animal experiments.

In collaboration with the Animal Welfare Information Center at the US Department of Agriculture in Beltsville, USA has produced a database which provides an overview of guidelines, databases, journals, email lists, regulations and policies which may help researchers to implement the 3Rs when planning research that may involve animals. The database is called 3R Guide.

The aim of 3R Guide is to provide a 'one-stop shop' for researchers who need to gain an overview of available 3R resources.

NORINA is an English-language database containing information on over 3,500 audiovisual aids that may be used as alternatives or supplements to the use of animals in education and training, including dissection alternatives, at all levels from Junior School to University.  The information in the database has been collected from 1991 onwards.

The Classic AVs database complements NORINA by providing information on audiovisual products produced some years ago, using technology which has been surpassed by modern digital techniques. We offer this collection for those who wish to continue to use classic technology.

EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation. 

Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.

The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan 
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators