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Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.