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University Biomedical Services (UBS)

 

General Database Information

3Rs Searches and Microsite-Canadian

This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.

Topic: Search tools and databases

The Macaque Website

The Macaque Website is a free resource for everyone who works with, or is interested in, laboratory macaques: animal care staff and technicians, facility managers, veterinarians, researchers, students, policy makers and IACUC/AWERB members. Developed by the UK’s National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), this site provides referenced information and practical guidance on the natural history and behaviour of macaques, their care and management in captivity, and ways to assess their welfare.

Topic: Other Resources

NIH LINCS Project

By generating and making public data that indicates how cells respond to various genetic and environmental stressors, the LINCS project will help us gain a more detailed understanding of cell pathways and aid efforts to develop therapies.

Topic: Search tools and databases

Zika Experimental Science Team (ZEST)

Welcome to the Zika experimental science team (ZEST) data portal. Given the urgency of the ongoing Zika virus epidemic, we are making our study results available in real-time. Each study and its available data are shown.

Topic: Search tools and databases

Procedures With Care

Procedures with Care Website by Newcastle University, NC3Rs and IAT, provides a series of resources to support the adoption of best practice for commonly used procedures in animal research. The focus is on rats and mice but further material will be added to expand the range of techniques and species in the future.   

Topic: Other Resources

Europe PubMed Central (Europe PMC)

Has over 5 million more abstracts than PubMed.

Topic: Search tools and databases

The Allen Brain Observatory

The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines. 

Topic: Search tools and databases, Teaching

Searching for 3Rs Information- Published Literature Sources

There is a legal and ethical obligation to reduce the numbers of animals in research and to enhance the welfare of those that are used. This has led to an increased need for access to information on this topic. To help meet these obligations, members of the UK Pharmaceutical Industry set up a working party of information experts (I3R) with the aim "to encourage the development of best practice in the provision and retrieval of information on alternatives to animals in pharmaceutical R&D with special reference to Refinement, Reduction and Replacement (3Rs)." 

Topic: Other Resources

PubMed

PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

Topic: Search tools and databases

INFRAFRONTIER 

INFRAFRONTIER is the European Research Infrastructure for phenotyping and archiving of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using the mouse model.

 

Topic: Search tools and databases

ARRIVE Guidelines

ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies.

Topic: Other Resources

TextBase

TextBase is a collection of information on textbooks within the field of laboratory animal science and related areas.

Topic: Search tools and databases

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