The Foundation for Liver Research UK was established in 1974 to develop and extend research into diseases of the human liver and to enhance medical research generally.
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CLDF supports a wide range of projects, including clinical and laboratory-based research, lately moving into social research which looks at topics such as how to improve quality of life.
General Database Information
EU 3Rs databases-The protection and welfare of animals is an area covered by a wide range of EU legislation. This includes the protection of wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Animal studies, whether for the development or production of new medicines, for physiological studies, for studying environmental effects or for the testing of chemicals or new food additives, has to be carried out in compliance with EU legislation.
Welcome to the Experimental Design Assistant, a free resource from the NC3Rs to support researchers in the planning of animal experiments - ensuring robust study design and reliable and reproducible findings.
The EDA consists of a web application and a supporting website; benefits include:
•The ability to build a stepwise visual representation of your experiment
•Feedback and advice on your experimental plan
•Dedicated support for randomisation, blinding and sample size calculation
•Practical information to improve knowledge of experimental design
•Improved transparency of your experimental design, allowing you to share and discuss your plan with colleagues and collaborators
Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.
Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.
The Biosciences Federation Animal Science Group was established in December 2002 and launched in September 2003 as an umbrella organisation to promote interaction within the biosciences community, particularly in areas of research and teaching; to provide information to assist the formulation of scientific policy; and, perhaps most challenging of all, to debate the ethical issues surrounding recent advances in the biosciences (see previous report by Nancy Rothwell).
Find Human tissue samples online using the UKCRC Tissue Directory.
This section of the Three Rs microsite provides useful links and information to help visitors easily find a wide range of resources.
Journal of Applied Animal Welfare Science (JAAWS) is a US journal that publishes articles, commentaries, and brief research reports on methods of experimentation, husbandry and care that demonstrably enhance the welfare of all nonhuman animals.
By generating and making public data that indicates how cells respond to various genetic and environmental stressors, the LINCS project will help us gain a more detailed understanding of cell pathways and aid efforts to develop therapies.