3Rs - search page

Has over 5 million more abstracts than PubMed.

The issues addressed in this Report have been a subject of intense public debate over at least the past four hundred years. Feelings are strong on all sides of the issues, and in recent years reports of violent action against those conducting animal research in the UK have brought the matter to the forefront of public attention.

The Allen Brain Observatory presents the first standardized in vivo survey of physiological activity in the mouse visual cortex, featuring representations of visually evoked calcium responses from GCaMP6-expressing neurons in selected cortical layers, visual areas and Cre lines. 

ALTBIB is a search tool that retrieves PubMed citations on alternatives to the use of live vertebrates in biomedical research and testing. It includes citations from published articles, books, book chapters, and technical reports. It also provides links to news sources and additional resources on alternatives to animal testing.

A wide variety of topics are covered, including biologics and vaccines, carcinogenesis, cytotoxicity, ecotoxicity, genotoxicity, hepatic/renal toxicity, immunotoxicity/immunology, neurotoxicity, ocular toxicity, pharmacokinetic/mechanistic studies, pyrogenicity, pulmonary toxicity, quantitative structure activity relationship (QSAR), reproductive and developmental toxicity, skin toxicity, and animal welfare.

PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

INFRAFRONTIER is the European Research Infrastructure for phenotyping and archiving of model mammalian genomes. The INFRAFRONTIER Research Infrastructure provides access to first-class tools and data for biomedical research, and thereby contributes to improving the understanding of gene function in human health and disease using the mouse model.

TextBase is a collection of information on textbooks within the field of laboratory animal science and related areas.

Guiding principles on good practice for Animal Welfare and Ethical Review Bodies (2015) (PDF 1.76MB). Developed and published jointly by the RSPCA and the Laboratory Animal Science Association (LASA), this resource aims to help in the efficient and effective operation of local animal welfare and ethical review bodies.

The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.