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IMPROVE-ing Animal Welfare in Experimental Stroke Research

Over the last two years, representatives from the UK’s stroke research community have been working, in a collaboration led by the NC3Rs, to improve the welfare and increase the scientific value of rodent models of stroke. The findings from the collaboration - The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)  have been published in the Journal of Cerebral Bloodflow and Metabolism.

Topic: Cardiology

Liverpool University Vetschool Cardiology Department
Topic: Cardiology

Penn Vet School Cardiology Research
Topic: Cardiology

Journal of Veterinary Cardiology
Topic: Cardiology

Animal Research in Pediatric Cardiology and Cardiac Surgery Paper and Pediatric Journal
Topic: Cardiology

JACC: Cardiovascular Interventions Open Access Journal
Topic: Cardiology

General Database Information

CAAT-Europe (Centre of Alternatives to Animal Testing)
Topic: Alternative methods, Information on drugs and diseases

TextBase

TextBase is a collection of information on textbooks within the field of laboratory animal science and related areas.

Topic: Search tools and databases

CAMARADES

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies. 

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial. 

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.

Topic: Other Resources

Frame Training Schools
Topic: Search tools and databases

UCDavis Centre for Animal Alternatives Information

The mission of the Centre is to provide leadership in matters relevant to animal welfare, focusing on the appropriate and humane care, husbandry, and management of animals.

Topic: Alternative methods

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