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3Rs

NORINA (A Norwegian Inventory of Audiovisuals)

NORINA is an English-language database containing information on over 3,500 audiovisual aids.

Topic: Replacement

Isogenic Strains

Isogenic strains (inbred strains and F1 hybrids) are like immortal clones of genetically identical individuals. The same genotype can be reproduced indefinitely. They have already made a substantial contribution to biomedical research. 

Topic: Reduction

American Fund for Alternatives to Animal Research (AFAAR)

AFAAR first helped make history by funding a landmark alternative to the infamous Draize rabbit eye test, later adopted by some major product and cosmetics companies.

Topic: Replacement

Medical Advances Without Animals Trust (MAWA)

MAWA's aim is to advance medical science to improve human health and therapeutic outcomes without using animals or animal products.

Topic: Replacement

Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Topic: Reduction

European Consensus-Platform for Alternatives (ECOPA)

The primary aim of ECOPA is to promote "the three Rs" (Replacement, Reduction and Refinement) in the use of animals in research, testing, education and training in Europe.

Topic: Replacement

SABRE Research UK

Systematic reviews: Evidence from animal research is considered by researchers to be of the lowest quality in medical research.

Topic: Reduction

Mandatory Alternatives Petition (US)

The Mandatory Alternatives Petition seeks to change the way drug testing is done in laboratories before drugs are tested on people.

Topic: Replacement

Using 3D Cell Models to Screen Out Ineffective Agents Before Animal Studies

Scientists at the ICR are growing spheres of cancer cells in the laboratory which are designed to mimic the properties of solid tumours.

Topic: Replacement

Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

Topic: Reduction

FRAME-Alternatives Lab

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

Topic: Replacement

New Tools for The Generation of peptide- and Antibody-Based Ligands in Vitro: Reduction of Antibody Production in Experimental Animals
Topic: Reduction

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