3Rs - search page

World leader in innovations without laboratory animals by 2025. That is the aim of the Dutch Minister for Agriculture, Martijn van Dam. In March 2016, the Minister asked the Netherlands National Committee for the protection of animals used for scientific purposes (NCad) to draw up a schedule for the phasing out of animal procedures.

‘Research integrity’ is an overarching term relating to the standards to which research is done. It requires every individual to acknowledge their responsibilities as well as being accountable for adhering to legal and ethical principles. 

Sabre offers ten recommendations and a strategy.They define these reccomendations (the 10Rs+) as RESPOND, REPLICATE, REGISTER, REPORT, RECORD, REVIEW, REGULATE, REAPPRAISE, RATIONALISE, REINVENT, REPRESENT. A word document with further information on the 10Rs+ (in a table) is available to download at the bottom of the page.

"The Design of Animal Experiments" is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively.

The PETA International Science Consortium Ltd. promotes non-animal research methods and coordinates the scientific and regulatory expertise of its members. With an eye toward championing the best non-animal methods and replacing tests on animals, the Science Consortium brings scientific expertise and extensive knowledge of the international regulatory environment to the development of testing protocols.

This section contains a selection of resources highlighting the alternatives to using animals in research, testing and teaching.

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

Kirkstall are a biotechnology company specialising in products and services supporting in-vitro cell culture research and the development of routine in vitro testing.

Establishment of a novel system for the production of large numbers of mouse basophils in vitro.

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

The Guide has specifically been developed to support untrained database users in finding high quality information on relevant alternative strategies and methods to animal experiments from the wide range of sources available on the web. The Guide provides examples of search procedures, suggested search terms and user guidance.  Target users are scientists, national authorities involved in animal protection and ethical committees verifying that all possible alternatives have been considered before conducting animal experiments.