3Rs - search page

Kirkstall are a biotechnology company specialising in products and services supporting in-vitro cell culture research and the development of routine in vitro testing.

Establishment of a novel system for the production of large numbers of mouse basophils in vitro.

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

The Guide has specifically been developed to support untrained database users in finding high quality information on relevant alternative strategies and methods to animal experiments from the wide range of sources available on the web. The Guide provides examples of search procedures, suggested search terms and user guidance.  Target users are scientists, national authorities involved in animal protection and ethical committees verifying that all possible alternatives have been considered before conducting animal experiments.

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

In the regulatory assessment of chemicals (e.g. under REACH), (Q)SAR models are playing an increasingly important role in predicting properties for hazard and risk assessment.

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

Silabe offers a large range of NonHuman Primate bioproducts to academic research institutes and companies in the field of Science and Health.

NORINA is an English-language database containing information on over 3,500 audiovisual aids.

Below are articles on the subject of Alternatives. If you can't see what you are looking for other categories are displayed on the left under 'Our Quick Links'.

The goal of this project was to develop and implement a harmonized guideline for ideal and maximum dose volumes for various routes for the most common laboratory animals in biomedical research.