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3Rs

The PETA International Science Consortium Ltd (PISC)

The PETA International Science Consortium Ltd. promotes non-animal research methods and coordinates the scientific and regulatory expertise of its members. With an eye toward championing the best non-animal methods and replacing tests on animals, the Science Consortium brings scientific expertise and extensive knowledge of the international regulatory environment to the development of testing protocols.

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Anzccart-Resource Bank Alternatives

This section contains a selection of resources highlighting the alternatives to using animals in research, testing and teaching.

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Reducing Mouse Numbers by Measuring Tumour Size Non-Invasively

Scientists at the ICR are increasingly using non-invasive methods to measure the size of tumours in mice – allowing the same mouse to be assessed several times and reducing the overall numbers

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Kirkstall

Kirkstall are a biotechnology company specialising in products and services supporting in-vitro cell culture research and the development of routine in vitro testing.

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3R-INFO-BULLETIN Swiss 3Rs

Establishment of a novel system for the production of large numbers of mouse basophils in vitro.

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Ex Vivo Culture Platform for Assessment of Cartilage Repair Treatment Strategies

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair strategies to reduce the high number of animal experiments.

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The EURL ECVAM Search Guide on Alternative Methods

The Guide has specifically been developed to support untrained database users in finding high quality information on relevant alternative strategies and methods to animal experiments from the wide range of sources available on the web. The Guide provides examples of search procedures, suggested search terms and user guidance.  Target users are scientists, national authorities involved in animal protection and ethical committees verifying that all possible alternatives have been considered before conducting animal experiments.

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Research Animal resources (US)

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

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Animal Tissue Database

Designed to facilitate sharing-SEARCH and SEARCHBreast provide scientists with choices when determining the most robust and relevant models to use when studying human disease.

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EURL ECVAM QSAR Model Inventory of the Commission’s Joint Research Centre (JRC)

In the regulatory assessment of chemicals (e.g. under REACH), (Q)SAR models are playing an increasingly important role in predicting properties for hazard and risk assessment.

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RSPCA-Useful Alternative Approaches

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

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Simian Laboratory Europe (Silabe)

Silabe offers a large range of NonHuman Primate bioproducts to academic research institutes and companies in the field of Science and Health.

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