The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.
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3Rs
Ethical Science Education (Library of Alternatives for Disection)
US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.
Topic: Replacement
Plan to Replace Animal Use Shared at Public Forum
Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.
Topic: Replacement
Alternatives-NIH-USA-ICCVAM-US
A website with explanations and sources of alternatives.
Topic: Replacement
Research Animal resources (US)
Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.
Topic: Replacement
International Cooperation on Alternative Test Methods (ICATM)
To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations in order to ensure worldwide acceptance.
Topic: Replacement
Alternatives Test Methods Table-Canadian 3Rs Microsite
The Alternative Test Methods Table is a resource for investigators and regulators on the validation and regulatory status of alternatives to animal-based regulatory test methods.
Topic: Replacement
RSPCA-Useful Alternative Approaches
The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.
Topic: Replacement
General Database Information
Films showing Handling and Basic Techniques in Common Laboratory Animal Species
Produced by Norecopa containing sort films, which alternatively can be viewed as slide series, illustrating common techniques. It is in English and free of charge.
Topic: Other Resources
Global List of Guidelines
The website is maintained by Norecopa. It covers all Three Rs, is in English and free of charge.
Topic: Other Resources
Guidelines On the Care and Use of Fish in Research
The website is maintained by Norecopa. It covers all Three Rs, is in English and free of charge.
Topic: Other Resources
Guidelines for "Good Scientific Practice"
These reccomendations are provided by Deutsche Forschungsgemeinschaft and are available in English. They may apply for a Three R information retrieval and the way, the retrieved information is processed and discussed in the project applications (to safeguard transparency, etc.).
Topic: Other Resources