3Rs - search page

The FRAME lab uses cells derived from human tissues to produce biologically relevant in vitro models of human organs, which behave and respond in the way they would in the body.

US-Founded in 1895, the New England Anti-Vivisection Society (NEAVS) is a Boston-based, national animal advocacy organization.

Representatives of federal agencies invited the public to the annual meeting, held at the National Institutes of Health (NIH) in Bethesda, Maryland.

A website with explanations and sources of alternatives.

Appendix A of the Animal Usage Form asks for the methods used to search for alternatives to procedures that may cause more than slight pain or distress to animals.

To establish international cooperation in the critical areas of validation studies, independent peer review, and development of harmonized recommendations in order to ensure worldwide acceptance.

The Alternative Test Methods Table is a resource for investigators and regulators on the validation and regulatory status of alternatives to animal-based regulatory test methods.

The RSPCA list a number of Alternative approaches: the use of isolated cells and tissues, using computers and mathematics to model biological processes and predict the effects of chemicals and drugs, designing ways of doing experiments safely in human volunteers, using simple organisms, such as bacteria, to study basic biological processes
exploring new advanced technologies such as robotics, molecular techniques, tissue engineering and "organs-on-microchips", not doing the experiment at all is one option - we encourage greater consideration of whether animal use could be avoided through more critical ethical review.

The Xenopus Model Welfare Organization will make the use of xenopus as a model organism better by promoting model specific, species specific knowledge and making that knowledge readily available to all stakeholders, including researchers, animal care supervisors, veterinarians, IACUC’s, and government oversight entities. It will influence the care, well-being, and welfare of xenopus as a model for years to come. It will be a compassionate entity that supports the care of xenopus frogs in research institutions and supports the people using xenopus by promoting science based, practical knowledge that can be used by all.

Xenbase's mission is to provide the international research community with a comprehensive, integrated and easy to use web based resource that gives access the diverse and rich genomic, expression and functional data available from Xenopus research. Xenbase also provides a critical data sharing infrastructure for many other NIH-funded projects, and is a focal point for the Xenopus community. In addition to our primary goal of supporting Xenopus researchers, Xenbase enhances the availability and visibility of Xenopus data to the broader biomedical research community.