3Rs - search page

EPISKIN, world leader in tissue engineering, offers Human Reconstructed Tissues to the global scientific community - academic and industry - to support research and development activities in Safety and Efficacy

The ZEBET database is mainly designed to support the examination of the imperative nature of animal experiments by providing information on possible alternative methods. 

Sabre offers ten recommendations and a strategy.They define these reccomendations (the 10Rs+) as RESPOND, REPLICATE, REGISTER, REPORT, RECORD, REVIEW, REGULATE, REAPPRAISE, RATIONALISE, REINVENT, REPRESENT. A word document with further information on the 10Rs+ (in a table) is available to download at the bottom of the page.

Animal Free Research UK funds research that directly impacts the replacement of animals in biomedical research. Their aim is the replacement of animals in fundamental biomedical research as well as proving that valuable human-relevant science can take place with the use of non-animal methods.

The Guide has specifically been developed to support untrained database users in finding high quality information on relevant alternative strategies and methods to animal experiments from the wide range of sources available on the web. The Guide provides examples of search procedures, suggested search terms and user guidance.  Target users are scientists, national authorities involved in animal protection and ethical committees verifying that all possible alternatives have been considered before conducting animal experiments.

This section contains a selection of resources highlighting the alternatives to using animals in research, testing and teaching.

Proceeding can be downloaded from the 10th World Congress on Alternatives and Animals in the Life Sciences- held 20th-24th August 2017

In the regulatory assessment of chemicals (e.g. under REACH), (Q)SAR models are playing an increasingly important role in predicting properties for hazard and risk assessment.

Official Journal of the International Society for Applied Ethology (ISAE) An international journal reporting on the application of ethology to animals managed by humans.

Laboratory Animals is an international journal of laboratory animal science and welfare. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.

Laboratory Animals publishes papers dealing with all aspects of the use of animals in biomedical research, including: new animal models; laboratory animal microbiology; clinical case reports; descriptions of new or improved research techniques; reports on the influence of environmental and other variables on research results; descriptions of techniques which offer replacements for in vivo models; and basic data characterizing the haematology, biochemistry or pathology of new or existing animal models. Papers describing work which involves a reduction in the number of animals that need to be used; or which replace animals with in vitro alternatives; or which represent a significant refinement in methodology, leading to improvements in the welfare or wellbeing of the animals used, are especially encouraged.

Journal of Applied Animal Welfare Science (JAAWS) is a US journal that publishes articles, commentaries, and brief research reports on methods of experimentation, husbandry and care that demonstrably enhance the welfare of all nonhuman animals.

The official journal of the Institute of Animal Technology and of the European Federation of Animal Technologists (EFAT).Animal Technology and Welfare aims to be the medium for animal technologists and all those concerned with the care and welfare of animals used for research purposes to communicate ‘best practice. ATW especially aims to promote and develop the 3Rs particularly in respect of Refinement.

More importantly, ATW promotes the generally accepted ‘4th R’, Responsibility. The responsibility that all animal technologists have in ensuring dissemination of ‘best practice’ to every institution using animals in research. ATW enjoys a unique position as the scientific publication for the leading organisations (IAT and EFAT) for the welfare of animals in research.