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University Biomedical Services (UBS)

 

3Rs

RSPCA Implementing the 3Rs

The RSPCA  strongly promote fuller implementation of all 3Rs, and they recognise the work done by other bodies to develop and validate humane alternatives, and to address the current crisis with reproducibility and translatability in the life sciences.

 

  • Replacement: methods which avoid or replace animal use - our principal goal
  • Reduction: ensuring that the minimum number of animals is used to answer the scientific question, using effective experimental design and statistical analysis to optimise numbers and avoid wasting animals
  • Refinement: reducing suffering and improving welfare throughout animals' lives, including procedures, housing, husbandry and care
Topic: Refinement

Pain and Laboratory Animals: Publication Practices for Better Data Reproducibility and Better Animal Welfare
Topic: Refinement

RSPCA Reduce Suffering Welfare Assessment

The term ‘welfare assessment’ refers to monitoring animals for signs of pain, suffering and distress associated with procedures and their effects, as well as to the day-to-day assessment of all animals to see how they are coping with their environment and to detect health or welfare issues. Indicators of positive wellbeing, such as appropriate levels of grooming and social interaction, should also be included when devising welfare assessment protocols.

Topic: Refinement

Refinement of Blood Sampling-NC3Rs

Blood sampling can be stressful for laboratory animals because of the handling, restraint, anaesthesia or discomfort associated with a particular technique

Topic: Refinement

Discipline tool

Infectious Disease Research-Oxford
Topic: Respiratory

World Organisation For Animal Health (OIE)

The OIE is the intergovernmental organisation responsible for improving animal health worldwide.

Topic: Respiratory

Jax Phenotype-Respiratory
Topic: Respiratory

Network of Expertise on Animal Influenza- Offlu
Topic: Respiratory

Merck Manual-Flu
Topic: Respiratory

Future of Vaccination
Topic: Respiratory

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