This gateway provides a place for researchers funded by the NC3Rs to promote the 3Rs impact of their work, and publish rapidly, in an open and transparent manner.
3Rs
Maximising the 3Rs Impact of NC3Rs-Funded Research
Topic: Refinement
Guidelines for the Care and Use of Animals in Research and Teaching
Norecopa has constructed four databases, which together with all the text on this website can be searched simultaneously using the search field at the top of every page.
Topic: Refinement
Analgesia and Pain Assessment-NC3Rs
Considerable progress has been made over the last decade in preventing or alleviating pain. In particular, there is now considerable opportunity to minimise or eliminate pain following surgical procedures.
Topic: Refinement
Mouse Handling (NC3Rs)
Exploring alternatives to gavage for oral administration
Topic: Refinement
Species specific
Guidance on the Care and Use of Fish
Topic: Fish
Guidance for Procedures Involving Fish
Topic: Fish
RSPCA- Housing and Care of Aquatic Species
Topic: Fish
Zebrafish Genome Project
The Sanger Institute started the zebrafish genome sequencing project in 2001 and has generated several genome assemblies of the Tuebingen strain. After the release of Zv9, the zebrafish genome project joined the Genome Reference Consortium (GRC) for further improvement and ongoing maintenance. The GRC has now released a new reference assembly, GRCz11.
Topic: Fish
Fish Arthritis Research
According to a new study in eLife, arthritis is much more widespread in the animal kingdom than previously suspected.
Topic: Fish
NC3Rs- Quantifying the Potential of Skin Swabbing as a Refinement for DNA Sampling of Laboratory Fish
The recent development of skin swabbing techniques - which produce sufficient DNA for PCR amplification - potentially offers a refined procedure with enormous impact for fish welfare.
Topic: Fish
RSPCA- Guidance on the Housing and Care of Zebrafish
Topic: Fish